Knight C J, Warren J B
Department of Cardiology, Royal Brompton Hospital, London, UK.
J Cardiovasc Risk. 1995 Jun;2(3):180-8.
The root causes of atherosclerosis lie in cellular events that precede the clinical presentation of the disease by many years. The initiating events centre around the response of endothelial cells to chronic injury, such as that sustained in hypercholesterolaemia. These responses involve the activation, attachment and migration of leucocytes and platelets.
动脉粥样硬化的根本原因在于细胞事件，这些事件在该疾病临床表现出现的多年之前就已发生。引发事件主要围绕内皮细胞对慢性损伤的反应，比如在高胆固醇血症中所遭受的损伤。这些反应涉及白细胞和血小板的激活、黏附和迁移。
