De Martino L, Nazzaro C, Concilio S, Galdiero M
Institute of Microbiology, Faculty of Medicine, University of Naples, Italy.
J Submicrosc Cytol Pathol. 1995 Oct;27(4):445-9.
The effects of different doses of Salmonella typhimurium porins were investigated on human laryngeal epithelial (HEp-2) cells by fluorescence and transmission electron microscopy. The changes observed in microfilament organization suggested an involvement of cytoskeleton in the cell response. Furthermore, morphologic phenomena characterized by ultrastructural membrane modifications also involved the nuclear membrane.
通过荧光显微镜和透射电子显微镜研究了不同剂量的鼠伤寒沙门氏菌孔蛋白对人喉上皮(HEp-2)细胞的影响。在微丝组织中观察到的变化表明细胞骨架参与了细胞反应。此外,以超微结构膜修饰为特征的形态学现象也涉及核膜。