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[下肢血栓栓塞性动脉闭塞的导管介入治疗]

[Catheterization therapy of thromboembolic arterial occlusions of the lower extremities].

作者信息

Stanĕk F, Karetová D, Kvasnicka J, Krivánek J, Keclík R, Tesar D

机构信息

II. interní klinika 1. LF UK a VFN, Praha.

出版信息

Cas Lek Cesk. 1995 Aug 2;134(15):471-3.

PMID:7585863
Abstract

Thromboembolic occlusions of peripheral arteries may threaten the vitality of extremities and sometimes patients life. Till recently the main therapeutic method was Fogarty surgical thromboembolectomy. A less invasive procedure is systemic (intravenous) and local (intraarterial) thrombolysis. All these method have, however, certain disadvantages. A new approach to the treatment for acute and subacute occlusions of peripheral arteries represents catheter thromboembolectomy, which involves the following: a) Aspiration of thromboembolic material--percutaneous thrombembolextraction (PTEE), b) Local infiltration thrombolysis where the catheter penetrates through the occlusion while simultaneously administering a fibrinolytic agent, c) PTA of residual stenosis in case of thrombotic occlusion. A combination of these methods of treatment for thromboembolic occlusions of peripheral arteries is very effective and enables to use a small amount of thrombolytic agent. The thrombosis and the underlying atherosclerotic stenosis are resolved during the same session.

摘要

外周动脉血栓栓塞性闭塞可能会威胁肢体的活力,有时甚至会危及患者生命。直到最近,主要的治疗方法还是Fogarty外科血栓切除术。一种侵入性较小的方法是全身(静脉)和局部(动脉内)溶栓。然而,所有这些方法都有一定的缺点。一种治疗外周动脉急性和亚急性闭塞的新方法是导管血栓切除术,其包括以下内容:a)抽吸血栓栓塞物质——经皮血栓栓子切除术(PTEE),b)局部浸润溶栓,即导管穿过闭塞部位的同时给予纤维蛋白溶解剂,c)在血栓性闭塞情况下对残余狭窄进行经皮腔内血管成形术(PTA)。这些治疗外周动脉血栓栓塞性闭塞的方法联合使用非常有效,并且能够使用少量的溶栓剂。在同一次治疗过程中,血栓形成和潜在的动脉粥样硬化性狭窄都能得到解决。

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1
[Catheterization therapy of thromboembolic arterial occlusions of the lower extremities].[下肢血栓栓塞性动脉闭塞的导管介入治疗]
Cas Lek Cesk. 1995 Aug 2;134(15):471-3.
2
LYS-plasminogen shortens the duration of local thrombolytic treatment of peripheral arterial occlusions--a randomized controlled trial.赖氨酸纤溶酶原缩短外周动脉闭塞局部溶栓治疗的持续时间——一项随机对照试验。
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