Tan A J, He S P, Huang M X
Department of Epidemiology, Tongji Medical University, Wuhan.
Zhonghua Liu Xing Bing Xue Za Zhi. 1995 Aug;16(4):199-202.
In order to discover the relationship between dietary nutrients intake and risk of lung cancer 1:1 matched case-control study on 156 recent histologiclly diagnosed primary lung cancer patients and 156 patients with respiratory tumour and other related diseases as controls, was conducted in Wuhan. All cases and controls were asked to participate in the nutritional assessment program and a food frequency questionnaire containing 64 food items was filled in. The findings showed that there was a statistically significant difference between dietary intake of beta-carotene between the two groups (2877.13 +/- 393.43 vs. 3445 +/- 430.98 micrograms/day). Having controled the confounding factor of cigarette smoking, a significant linear trend for lower dietary carotene intake toward higher lung cancer risk was observed.
为了探究膳食营养素摄入量与肺癌风险之间的关系，在武汉对156例近期经组织学确诊的原发性肺癌患者和156例患有呼吸道肿瘤及其他相关疾病的患者作为对照进行了1:1匹配病例对照研究。所有病例和对照均被要求参与营养评估项目，并填写一份包含64种食物的食物频率问卷。结果显示，两组之间β-胡萝卜素的膳食摄入量存在统计学显著差异（2877.13±393.43与3445±430.98微克/天）。在控制了吸烟这一混杂因素后，观察到膳食胡萝卜素摄入量越低，肺癌风险越高的显著线性趋势。
