Hakim J G, Kiire C F, Weinig M, Gudza I, Makunike R T, Muronda C, Siziya S
Department of Medicine, University of Zimbabwe, Harare, Zimbabwe.
Cent Afr J Med. 1995 Aug;41(8):237-41.
Fine needle aspiration (FNA) of the liver without ultrasound guidance was performed on 110 patients with hepatocellular carcinoma (HCC). The median age was 52 years, with a range of 16 to 86 years. There were 90 males and 20 females (a male: female ratio of 4.5:1), with a median age of 51.5 years (range 16 to 86 years) and 55.5 years (range 17 to 72 years) respectively. FNA was reported as showing malignancy in 92 (84 pc, 95 pc CI 77 to 91 pc) patients; 80 (73 pc) were definite HCC, 12 (11 pc) were malignant unspecified, seven (6 pc) were suspicious of malignancy, seven (6 pc) had no malignant cells and four (4 pc) were non-diagnostic. The only complication observed was dizziness in one patient. We conclude that FNA of the liver for the diagnosis of HCC is a safe, simple and accurate procedure which can be undertaken in settings that would otherwise not be suitable for formal liver biopsy.
对110例肝细胞癌（HCC）患者在无超声引导下进行了肝脏细针穿刺抽吸（FNA）。中位年龄为52岁，范围为16至86岁。男性90例，女性20例（男：女比例为4.5：1），中位年龄分别为51.5岁（范围16至86岁）和55.5岁（范围17至72岁）。FNA报告显示92例（84%，95%CI 77至91%）患者为恶性；80例（73%）为确诊的HCC，12例（11%）为未明确的恶性肿瘤，7例（6%）怀疑为恶性，7例（6%）无恶性细胞，4例（4%）诊断不明确。观察到的唯一并发症是1例患者出现头晕。我们得出结论，用于诊断HCC的肝脏FNA是一种安全、简单且准确的操作，可在其他不适合进行正规肝活检的情况下进行。
