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鼻窦和鼻腔癌适形放疗对眼部的晚期影响。

Late effects on the eye of conformation radiotherapy for carcinoma of the paranasal sinuses and nasal cavity.

作者信息

Morita K, Kawabe Y

出版信息

Radiology. 1979 Jan;130(1):227-32. doi: 10.1148/130.1.227.

DOI:10.1148/130.1.227
PMID:758655
Abstract

Sixty patients with carcinoma of the paranasal sinuses and nasal cavity were treated with conformation radiotherapy technique (an improved moving-field technique). Only 28 were suitable for long-term follow-up with regard to eye complications. All patients receiving more than 5,800 rads in 6 weeks (1,700 reu in cumulative-radiation-effect dose) had strong panophthalmia with corneal ulceration within 2 years of radiotherapy. Of 21 eyes receiving 800--1,700 reu (2,800--5,400 rads in 6 weeks), 18 experienced visual disturbance from radiation cataracts and 3 equivocal changes at postirradiation intervals of 5 years. No patient receiving less than 800 reu (2,800 rads in 6 weeks) showed such complications.

摘要

60例鼻窦和鼻腔癌患者采用适形放疗技术(一种改良的移动野技术)进行治疗。关于眼部并发症,只有28例适合长期随访。所有在6周内接受超过5800拉德(累积辐射效应剂量为1700雷姆)的患者在放疗后2年内出现严重全眼球炎并伴有角膜溃疡。在接受800 - 1700雷姆(6周内2800 - 5400拉德)的21只眼中,18只在放疗后5年出现放射性白内障导致的视力障碍,3只出现不明确的变化。接受少于800雷姆(6周内2800拉德)的患者未出现此类并发症。

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