Gawne-Cain M L, Smith E, Darby M, Given-Wilson R
Department of Diagnostic Radiology, St George's Hospital, London, UK.
Clin Radiol. 1995 Oct;50(10):681-6. doi: 10.1016/s0009-9260(05)83312-4.
In a prospective study, use of serial ultrasound (US) for monitoring tumour response to pro-adjuvant chemotherapy was assessed in 16 patients. Comparison was made with mammographic and pathological tumour size measurements. Clinical and radiological response to treatment was assessed using UICC (International Union Against Cancer) criteria. Comparison of clinical and US response to treatment showed some agreement in 60% and disagreement in 40%. This was comparable with clinical versus mammographic responses (55% and 45%). Correlation between calliper and pathological measurement was similar to that between US and pathological measurement (r = 0.51, P = 0.05; r = 0.50, P < 0.05). Mammography showed poorer correlation (NS). For assessment of final tumour size, US clinical measurements were comparable and better than mammography. US may be a useful tool in monitoring the response of breast tumours to pro-adjuvant therapy.
在一项前瞻性研究中，对16例患者使用连续超声（US）监测肿瘤对新辅助化疗的反应进行了评估。将其与乳房X线摄影和病理肿瘤大小测量结果进行了比较。使用国际抗癌联盟（UICC）标准评估治疗的临床和放射学反应。临床与超声治疗反应的比较显示，60%有一定一致性，40%不一致。这与临床与乳房X线摄影反应（55%和45%）相当。游标卡尺测量与病理测量之间的相关性与超声与病理测量之间的相关性相似（r = 0.51，P = 0.05；r = 0.50，P < 0.05）。乳房X线摄影显示相关性较差（无显著性差异）。对于最终肿瘤大小的评估，超声临床测量结果相当且优于乳房X线摄影。超声可能是监测乳腺肿瘤对新辅助治疗反应的有用工具。
