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[采用深度低温和心脏停搏并持续输注血液停搏液进行胸主动脉和胸腹主动脉瘤手术]

[Surgery of thoracic and thoraco-abdominal aneurysms using deep hypothermia and cardiovascular arrest with continuous administration of blood cardioplegia].

作者信息

Grabenwöger M, Ehrlich M, Simon P, Grimm M, Laufer G, Havel M

机构信息

Abteilung für Herz-Thorax-Chirurgie, Universitätsklinik für Chirurgie Wien.

出版信息

Chirurg. 1995 Sep;66(9):878-82.

PMID:7587559
Abstract

Between January 1991 and February 1993, 14 patients (3 female, 11 male) aged between 21 and 79 years (mean 50 years) underwent reconstruction of the thoracic (n = 7) and thoracoabdominal aorta (n = 7). Four patients had previously undergone operation of the ascending aorta, in 3 patients coronary artery by pass grafting was performed before. All patients were operated using cardiopulmonary bypass with continuous blood cardioplegia, hypothermic circulatory arrest (11 degrees C nasopharyngeal temperature, 0-EEG) and posterolateral exposure. All patent lower intercostal and lumbar arteries (Th3-L5) were reimplanted. The 30-day mortality after repair of the thoracic aorta was 0, after replacement of the thoracoabdominal aorta 28.5% (n = 2). One patient died 70 days after replacement of the thoracic aorta as a consequence of a perioperative stroke. None of the surviving 11 patients developed a permanent neurologic deficit, renal or cardiac dysfunction. The average intensive care stay was 6 days for patients after replacement of the thoracic and 18 days for patients after replacement of the thoracoabdominal aorta. Our results indicate the method of elective hypothermia and circulatory arrest effective in spinal cord protection. The increase in the tolerable duration of spinal cord ischemia supports the reimplantation of all intercostal and lumbar vessels.

摘要

1991年1月至1993年2月期间,14例患者(3例女性,11例男性),年龄在21至79岁之间(平均50岁),接受了胸主动脉(n = 7)和胸腹主动脉(n = 7)的重建手术。4例患者此前接受过升主动脉手术,3例患者之前进行过冠状动脉搭桥手术。所有患者均在体外循环下进行手术,采用持续血液心脏停搏、低温循环停止(鼻咽温度11摄氏度,脑电图呈0-EEG)和后外侧暴露。所有通畅的下肋间动脉和腰动脉(Th3-L5)均进行了再植。胸主动脉修复后的30天死亡率为0,胸腹主动脉置换后的死亡率为28.5%(n = 2)。1例患者在胸主动脉置换70天后因围手术期中风死亡。11例存活患者均未出现永久性神经功能缺损、肾脏或心脏功能障碍。胸主动脉置换术后患者的平均重症监护停留时间为6天,胸腹主动脉置换术后患者为18天。我们的结果表明,选择性低温和循环停止方法在脊髓保护方面有效。脊髓缺血耐受时间的增加支持了所有肋间和腰血管的再植。

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