醋丁洛尔治疗室性早搏
Treatment of premature ventricular complexes with acebutolol.
作者信息
Aronow W S, Turbow M, Lurie M, Whittaker K, Van Camp S
出版信息
Am J Cardiol. 1979 Jan;43(1):106-8. doi: 10.1016/0002-9149(79)90052-3.
The effect of intravenous acebutolol versus saline solution on frequent premature ventricular complexes was evaluated in a double-blind, randomized study in 20 patients, including 3 with chronic obstructive pulmonary disease. Frequent premature ventricular complexes were abolished or reduced by 75% or more in none of 12 patients given saline solution but in 18 of 20 patients (90%) given acebutolol (P less than 0.001). This therapeutic effect of acebutolol persisted for at least 2.5 hours in 17 of 20 patients (85%), for at least 3.5 hours in 14 (70%) and for at least 4 hours in 8 (40%). Acebutolol was well tolerated by the three patients with chronic obstructive pulmonary disease. These data indicate that intravenous acebutolol is useful in the treatment of premature ventricular complexes.
在一项双盲、随机研究中，对20例患者（包括3例慢性阻塞性肺疾病患者）评估了静脉注射醋丁洛尔与生理盐水对频发室性早搏的影响。给予生理盐水的12例患者中，无一例频发室性早搏消失或减少75%以上，但给予醋丁洛尔的20例患者中有18例（90%）出现这种情况（P<0.001）。20例患者中有17例（85%）醋丁洛尔的这种治疗效果持续至少2.5小时，14例（70%）持续至少3.5小时，8例（40%）持续至少4小时。3例慢性阻塞性肺疾病患者对醋丁洛尔耐受性良好。这些数据表明静脉注射醋丁洛尔对治疗室性早搏有效。
Zotero 插件