Shu Z, Li J
Department of Adbominal Surgery, Nanjing General Hospital of PLA.
Zhonghua Wai Ke Za Zhi. 1995 May;33(5):279-81.
Thirty-two patients with major abdominal trauma were studied to evaluate the effects of total parenteral nutrition (TPN). There were 24 men and 8 women with average age of 31 years. Twenty-five cases of the group were recorded to have blunt trauma. Abdominal trauma index (ATI) was used to score the injury severity. Sixty-eight percent (22/32) of the patients had more than 15 of ATI and 25% (8/32) had the score over 25. TPN was given to 11 patients with complicated injuries of pancreas and duodenum, to 15 patients with small bowel fistula secondary to extended intestinal trauma, and to 6 patients with severe intraabdominal abscesses after injuries. The average period of TPN support was 26 days. Nutrients were perfused with 32-42 kcal/kg/d of nonprotein energy and 0.21-0.30g/kg/d of nitrogen. The results demonstrated that there were no changes in body weights. Weekly accumulative nitrogen balances increased significantly after the use of TPN. There were great increases of serum albumin, prealbumin, fibronectin and transferrin following TPN support. Blood sugar, cholesterol and triglyceride were in normal ranges. No TPN-related complication developed. All patients recovered uneventfully. It is concluded that the appropriate use of total parenteral nutrition can play an effective role in the treatment of severe abdominal traumatic patients.
对32例严重腹部创伤患者进行了研究,以评估全胃肠外营养(TPN)的效果。其中男性24例,女性8例,平均年龄31岁。该组中有25例记录为钝性创伤。采用腹部创伤指数(ATI)对损伤严重程度进行评分。68%(22/32)的患者ATI超过15分,25%(8/32)的患者评分超过25分。11例胰腺和十二指肠复合伤患者、15例因广泛肠创伤继发小肠瘘的患者以及6例伤后严重腹腔脓肿患者接受了TPN治疗。TPN支持的平均时间为26天。营养物质以32 - 42千卡/千克/天的非蛋白能量和0.21 - 0.30克/千克/天的氮进行灌注。结果显示体重无变化。使用TPN后每周累积氮平衡显著增加。TPN支持后血清白蛋白、前白蛋白、纤连蛋白和转铁蛋白大幅增加。血糖、胆固醇和甘油三酯均在正常范围内。未发生与TPN相关的并发症。所有患者均顺利康复。结论是,合理使用全胃肠外营养可在严重腹部创伤患者的治疗中发挥有效作用。