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“尾蚴样”细胞:转移性肿瘤移行细胞起源的细胞诊断线索?

"Cercariform" cells: a clue to the cytodiagnosis of transitional cell origin of metastatic neoplasms?

作者信息

Powers C N, Elbadawi A

机构信息

Department of Pathology, State University of New York, Health Science Center, Syracuse 13210, USA.

出版信息

Diagn Cytopathol. 1995 Jul;13(1):15-21. doi: 10.1002/dc.2840130105.

DOI:10.1002/dc.2840130105
PMID:7587869
Abstract

The "cercariform" cell is described as a distinct cytomorphologic clue that may be helpful in the diagnosis of metastatic transitional cell neoplasms, particularly low grade. This cell has a nucleated globular body and a cytoplasmic process with a nontapering, flattened, bulbous or fishtail-like end. The cercariform cell corresponds to intermediate cells in histologic and ultrastructural preparations of normal urothelium. The cercariform appearance is the result of pseudostratification of both normal and low-grade neoplastic urothelium. The unique features of cercariform cells make them readily distinguishable from neoplastic squamous cells as well as spindle cells of mesenchymal origin.

摘要

“尾蚴样”细胞被描述为一种独特的细胞形态学线索,可能有助于转移性移行细胞肿瘤的诊断,尤其是低级别肿瘤。这种细胞有一个有核的球状主体和一个细胞质突起,其末端无逐渐变细,呈扁平状、球状或鱼尾状。尾蚴样细胞对应于正常尿路上皮组织学和超微结构标本中的中间细胞。尾蚴样外观是正常和低级别肿瘤性尿路上皮假复层的结果。尾蚴样细胞的独特特征使其易于与肿瘤性鳞状细胞以及间充质来源的梭形细胞区分开来。

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