Rodin E, Litzinger M, Thompson J
Primary Children's Medical Center, University of Utah, Sandy, USA.
Epilepsia. 1995 Nov;36(11):1078-83. doi: 10.1111/j.1528-1157.1995.tb00465.x.
The EEGs of 39 children with focal or multifocal spikes were subjected to singular value decomposition (SVD) as provided by a commercial software program. We noted that in children with spikes but no clinical seizures the variance accounted for by the first component averaged 91.9%, whereas in children with seizures it was 68.0% (p < .001). The first component accounted for 85.4% in children with single spike foci, for 71.5% in those with multifocal spikes, and for 61.4% (p < 0.002) in those with both focal spikes and generalized spike-wave complexes. Spikes in the frontal and frontopolar areas were the most complex, suggesting that at least in children they tend to be the partial expression of a generalized seizure tendency rather than a result of strictly local pathology.
39例有局灶性或多灶性棘波的儿童脑电图，采用商业软件程序提供的奇异值分解（SVD）进行分析。我们注意到，有棘波但无临床发作的儿童中，第一成分解释的方差平均为91.9%，而有发作的儿童中为68.0%（p <.001）。单棘波灶儿童中第一成分占85.4%，多灶性棘波儿童中占71.5%，局灶性棘波和全身性棘慢复合波儿童中占61.4%（p < 0.002）。额区和额极区的棘波最为复杂，这表明至少在儿童中，它们往往是全身性发作倾向的部分表现，而非严格局部病变的结果。
