Adams W P, Donahoe P K
Arch Surg. 1979 Jan;114(1):79-81. doi: 10.1001/archsurg.1979.01370250081017.
Heterotopic salivary gland tissue in branchial cleft cysts in the upper part of the neck reputedly differentiates from the epithelial lining of the cyst. We describe a patient with salivary gland tissue found in the lower part of the neck. How salivary gland tissue finds its way to the lower neck is obscure. It is conceivable that the tissue originated from a precervical sinus or cervical vesicle, a distinct embryologic structure that forms in the lower part of the neck between the second branchial arch and the upper thoracic wall, but that normally disappears by the time of birth. The epithelial lining of the cervical vesicle is thought to be associated with the early development of the glossopharyngeal and vagus nerves. Salivary gland tissue may differentiate from the epithelial lining of cervical vesicles and nurture the growing nerves by nerve growth factor elaboration.
据报道，颈部上方鳃裂囊肿中的异位唾液腺组织源自囊肿的上皮内衬。我们描述了一名在颈部下方发现唾液腺组织的患者。唾液腺组织如何到达颈部下方尚不清楚。可以想象，该组织起源于颈前窦或颈泡，这是一种独特的胚胎结构，形成于颈部下方第二鳃弓和上胸壁之间，但通常在出生时就消失了。颈泡的上皮内衬被认为与舌咽神经和迷走神经的早期发育有关。唾液腺组织可能从颈泡的上皮内衬分化而来，并通过分泌神经生长因子来滋养生长中的神经。
