Madrigal V, Alonso J, Bureo E, Figols F J, Salesa R
Department of Pediatrics, Hospital Universitario Marqués de Valdecilla, Spain.
Eur J Clin Microbiol Infect Dis. 1995 Jul;14(7):601-3. doi: 10.1007/BF01690733.
A fatal case of meningoencephalitis caused by Scedosporium inflatum (Scedosporium prolificans) in a 5-year-old boy with acute myeloblastic leukemia who was given intrathecal treatment is reported. Itraconazole treatment was ineffective. The fungus was identified on brain sections at autopsy and was not observed in any other organ. As no other portal of entry was detected, meningoencephalitis may have originated via direct introduction of the fungus at therapeutic lumbar puncture.
报告了一例5岁急性髓细胞白血病男孩鞘内治疗后发生由膨胀瓶霉（多育瓶霉）引起的脑膜脑炎致死病例。伊曲康唑治疗无效。尸检时在脑切片上鉴定出该真菌，其他任何器官均未发现。由于未检测到其他感染途径，脑膜脑炎可能是在治疗性腰椎穿刺时真菌直接引入所致。
