Vaccarino V, Borgatta A, Gallus G, Sirtori C R
Istituto di Scienze Farmacologiche, University of Milan, Italy.
Eur Heart J. 1995 Jun;16(6):761-9. doi: 10.1093/oxfordjournals.eurheartj.a060994.
A cross-sectional study of 2650 male and 751 female employees of the IBM company in the Milan area was conducted in 1987 to compare risk profiles for coronary heart disease between men and women and to analyse the awareness of risk status of people at risk. After age adjustment, the rate of cigarette smoking was higher in women (35%) than in men (25%). Other coronary heart disease risk factors were more common in men than in women. After controlling for age, 38% of the men and 19% of the women met the study criteria for hypertension, and 22% of the men and 17% of the women had high blood cholesterol. However, an analysis by age groups showed that, although in the younger age groups women had lower levels of cardiovascular risk factors, except smoking, compared to men, in the age brackets 50 or older women had similar or more adverse risk factor profiles than men. Of the people with hypertension, only 22% of the men and 19% of the women were aware of their hypertension, and only 2% of the men and 4% of the women had successful control by drugs. Even when subjects with mild hypertension were excluded, high proportions of undiagnosed and uncontrolled hypertension were found in both sexes. Of the individuals with serum cholesterol > or = 240 mg.dl-1, less than half of the men and less than 20% of the women were aware of their high blood cholesterol levels. Multiple risk factors were frequently present in the same individuals, especially among males and older women.(ABSTRACT TRUNCATED AT 250 WORDS)
1987年,对米兰地区IBM公司的2650名男性员工和751名女性员工进行了一项横断面研究,以比较男性和女性冠心病的风险状况,并分析高危人群对自身风险状况的认知情况。年龄调整后,女性吸烟率(35%)高于男性(25%)。其他冠心病危险因素在男性中比在女性中更常见。控制年龄因素后,38%的男性和19%的女性符合高血压研究标准,22%的男性和17%的女性患有高胆固醇血症。然而,按年龄组分析显示,尽管在较年轻年龄组中,女性除吸烟外的心血管危险因素水平低于男性,但在50岁及以上年龄组中,女性的危险因素状况与男性相似或更不利。在高血压患者中,只有22%的男性和19%的女性知道自己患有高血压,只有2%的男性和4%的女性通过药物成功控制了血压。即使排除轻度高血压患者,男女中仍有很大比例的高血压未被诊断和控制。在血清胆固醇≥240mg.dl-1的个体中,不到一半的男性和不到20%的女性知道自己的高胆固醇水平。多种危险因素经常出现在同一个体中,尤其是在男性和老年女性中。(摘要截选至250词)