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异位妊娠后的生殖潜能。

Reproductive potential after an ectopic pregnancy.

作者信息

al-Nuaim L, Bamgboye E A, Chowdhury N, Adelusi B

机构信息

Department of Obstetrics and Gynaecology, King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia.

出版信息

Fertil Steril. 1995 Nov;64(5):942-6. doi: 10.1016/s0015-0282(16)57906-0.

DOI:10.1016/s0015-0282(16)57906-0
PMID:7589638
Abstract

OBJECTIVE

To measure statistically how soon pregnancy can occur after an ectopic pregnancy (EP) so as to determine the cumulative pregnancy rate and the risk factors involved in nonpregnancy.

DESIGN

The risk of not getting pregnant after an EP (survivorship) was estimated for 120 patients followed up for up to 60 months using the actuarial life-table technique. The risk factors involved in nonpregnancy, abortions, or live births were analyzed, using Cox regression models.

SETTING

King Khalid University Hospital, Riyadh, Saudi Arabia.

RESULTS

There were 68 pregnancies over the study period, with a conception rate of 56.7%. Using the actuarial life table, the cumulative probability of not achieving pregnancy in a patient decreased sharply during the first 12 months, followed by a gradual decrease up to 48 months. The Cox regression analysis showed a correlation between pregnancy and two variables, namely, age and history of prior EP. The chances of a pregnancy resulting in abortion or live birth also correlated with the presence of prior infertility, pelvic inflammatory disease (PID), or postoperative complications.

CONCLUSION

Age and prior EP are important determinants in pregnancy rates after an EP. Similarly, history of PID, infertility, and postoperative complications are important risk factors in whether the pregnancy goes to term or ends in abortion.

摘要

目的

通过统计学方法测定异位妊娠(EP)后多快能再次怀孕,以确定累积妊娠率及未怀孕的相关风险因素。

设计

采用精算寿命表技术,对120例随访长达60个月的患者评估EP后未怀孕(生存情况)的风险。使用Cox回归模型分析未怀孕、流产或活产的相关风险因素。

地点

沙特阿拉伯利雅得市哈立德国王大学医院。

结果

在研究期间有68例妊娠,受孕率为56.7%。使用精算寿命表,患者未怀孕的累积概率在最初12个月内急剧下降,之后直至48个月逐渐下降。Cox回归分析显示妊娠与两个变量相关,即年龄和既往EP史。妊娠导致流产或活产的几率也与既往不孕、盆腔炎(PID)或术后并发症有关。

结论

年龄和既往EP是EP后妊娠率的重要决定因素。同样,PID史、不孕史和术后并发症是妊娠能否足月或流产的重要风险因素。

相似文献

1
Reproductive potential after an ectopic pregnancy.异位妊娠后的生殖潜能。
Fertil Steril. 1995 Nov;64(5):942-6. doi: 10.1016/s0015-0282(16)57906-0.
2
Multiple induced abortions as risk factor for ectopic pregnancy. A prospective study.多次人工流产作为异位妊娠的危险因素:一项前瞻性研究
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Long-term reproductive outcomes in women whose first pregnancy is ectopic: a national controlled follow-up study.首次妊娠为宫外孕的女性的长期生殖结局:一项全国性对照随访研究。
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Background factors of ectopic pregnancy. I. Frequency distribution in a case-control study.异位妊娠的背景因素。I. 病例对照研究中的频率分布
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Fertility following ectopic pregnancy with special reference to previous use of an intra-uterine contraceptive device (IUCD).宫外孕后的生育情况,特别提及既往宫内节育器(IUCD)的使用情况。
Acta Obstet Gynecol Scand. 1987;66(2):131-5. doi: 10.3109/00016348709083034.
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Epidemiology of ectopic pregnancy during a 28 year period and the role of pelvic inflammatory disease.28年间异位妊娠的流行病学及盆腔炎的作用
Sex Transm Infect. 2000 Feb;76(1):28-32. doi: 10.1136/sti.76.1.28.