Haller H, Petrović O, Rukavina B
Department of Obstetrics and Gynecology, Clinical Hospital Centre, University of Rijeka, Croatia.
Int J Gynaecol Obstet. 1995 Aug;50(2):159-63. doi: 10.1016/0020-7292(95)02423-a.
To test the usefulness of the fetal transverse cerebellar diameter/abdominal circumference (TCD/AC) ratio in predicting known small-for-gestational-age (SGA) infants.
The relationship between fetal TCD and AC throughout the second half of pregnancy was investigated in 635 well-dated, normal pregnancies and examined with regard to gestational age and infant birth weight percentiles.
One hundred eighteen (19%) fetuses were excluded due to inadequate visualization of the fetal cerebellum. A strong correlation was noted between gestational age determined by the last menstrual period and both fetal TCD (r2 = 0.91338) and AC (r2 = 0.89361) in fetuses with birth weights between the 10th and 90th percentiles (n = 407; mean 14.4, S.D. 1.2). Although the TCD/AC ratio showed a poor correlation with gestational age (r2 = 0.15788), a slight increase was noted during gestation. A TCD/AC ratio greater than 15.5 was present in 80% of SGA infants when measurements were performed within 1 week of delivery.
Fetal TCD/AC ratio as a gestational age-independent method could improve diagnostic sensitivity and specificity in the early detection of fetal growth abnormalities.
检测胎儿小脑横径与腹围比值(TCD/AC)在预测已知小于胎龄儿(SGA)中的作用。
对635例孕周准确的正常妊娠进行研究,观察妊娠后半期胎儿TCD与AC之间的关系,并根据孕周和婴儿出生体重百分位数进行分析。
118例(19%)胎儿因小脑显示不清被排除。在出生体重位于第10至90百分位数之间的胎儿(n = 407;平均14.4,标准差1.2)中,末次月经确定的孕周与胎儿TCD(r2 = 0.91338)和AC(r2 = 0.89361)之间均存在强相关性。虽然TCD/AC比值与孕周的相关性较差(r2 = 0.15788),但在孕期有轻微升高。在分娩前1周内进行测量时,80%的SGA婴儿TCD/AC比值大于15.5。
胎儿TCD/AC比值作为一种不依赖孕周的方法,可提高胎儿生长异常早期检测的诊断敏感性和特异性。