Dilmen G, Toppare M F, Turhan N O, Oztürk M, Işik S
Department of Radiology, Turkish Health and Therapy Foundation Medical Center, Ankara, Turkey.
Fetal Diagn Ther. 1996 Jan-Feb;11(1):50-6. doi: 10.1159/000264279.
In a prospective study of 330 pregnant women, measurements of the transverse cerebellar diameter (TCD), abdominal circumference (AC), biparietal diameter (BPD), head circumference (HC) and TCD/AC ratio and HC/AC ratio were obtained using conventional ultrasonography between 16th and 41st weeks of gestation. Measurement of BPD yielded a strong correlation with gestational age (r = 0.9880 and R2 = 0.9761) by cubic regression analysis. The measurement of TCD also had a very close relation with gestational age (r = 0.9767 and R2 = 0.9539). The ratio between TCD and AC was calculated and found to be 0.1436 +/- 0.0106 (SD) which remained fairly constant throughout pregnancy, while the BPD/AC ratio declined. The 5th and 95th percentiles for this ratio were 0.1279 and 0.1603. Ten of eleven fetuses with TCD/AC ratios exceeding 2 SD (0.1648) were found to have asymmetrical intrauterine growth retardation upon neonatal examination. It is demonstrated that both BPD and TCD measurements are reliable techniques that correlate well with gestational age, and the TCD/AC ratio is valuable in identifying babies with asymmetrical intrauterine growth retardation.
在一项对330名孕妇的前瞻性研究中，在妊娠第16周至41周期间使用传统超声测量了小脑横径（TCD）、腹围（AC）、双顶径（BPD）、头围（HC）以及TCD/AC比值和HC/AC比值。通过三次回归分析，BPD测量值与孕周有很强的相关性（r = 0.9880，R2 = 0.9761）。TCD测量值与孕周也有非常密切的关系（r = 0.9767，R2 = 0.9539）。计算得出TCD与AC的比值为0.1436 +/- 0.0106（标准差），在整个孕期保持相当稳定，而BPD/AC比值下降。该比值的第5和第95百分位数分别为0.1279和0.1603。在新生儿检查中，11例TCD/AC比值超过2个标准差（0.1648）的胎儿中有10例被发现有不对称性宫内生长受限。结果表明，BPD和TCD测量都是与孕周相关性良好的可靠技术，TCD/AC比值在识别不对称性宫内生长受限的婴儿方面具有重要价值。
