Griffiths F, Jones K
Department of Sociology and Social Policy, University of Durham, UK.
Fam Pract. 1995 Jun;12(2):163-5. doi: 10.1093/fampra/12.2.163.
Hormone replacement therapy is used for both menopausal symptoms and in prevention, but for the latter to be effective there may be a need to promote its use. Suitable strategies need to be informed by current practice. A postal questionnaire was therefore sent to 1649 women aged 20-69 years in Stockton-on-Tees to assess which women consider and take hormone replacement therapy. The response rate was 74%. Therapy had been considered by 346 (28%) women of whom 164 (47%) were premenopausal. It was taken by 20% of women aged 45-65 years. Users were more likely to have taken the contraceptive pill. Use of therapy by women with osteoporosis or cardiovascular disease, or with a family history of these, was low. As women used to the idea of taking hormone replacement therapy and accustomed to taking the contraceptive pill reach menopausal age there is likely to be an increase in uptake of therapy. By targeting the 'at risk' groups of women, the primary care team may be able to make most effective use of the therapy and their own resources for the prevention of osteoporosis and cardiovascular disease.
激素替代疗法既用于缓解更年期症状，也用于预防，但要使其在预防方面发挥有效作用，可能需要推广其使用。合适的策略需要依据当前的实际情况来制定。因此，向蒂斯河畔斯托克顿的1649名年龄在20至69岁之间的女性发放了邮寄调查问卷，以评估哪些女性会考虑并使用激素替代疗法。回复率为74%。346名（28%）女性考虑过使用该疗法，其中164名（47%）处于绝经前。45至65岁的女性中有20%使用过该疗法。使用者更有可能服用过避孕药。患有骨质疏松症或心血管疾病，或有这些疾病家族史的女性使用该疗法的比例较低。随着习惯服用激素替代疗法和避孕药的女性步入更年期，该疗法的使用量可能会增加。通过针对“高危”女性群体，基层医疗团队或许能够最有效地利用该疗法以及自身资源来预防骨质疏松症和心血管疾病。
