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[肝脾血管肉瘤合并腹腔积血及弥散性血管内凝血。动脉栓塞及化疗治疗]

[Hepatosplenic angiosarcoma complicated by hemoperitoneum and disseminated intravascular coagulation. Treatment by arterial embolization and chemotherapy].

作者信息

Tordjman R, Eugène C, Clouet O, Wesenfelder L, Collet C, Bergue A

机构信息

Unité d'Hêpato-Gastroentérologie, Centre Hospitalier Intercommunal, Poissy.

出版信息

Gastroenterol Clin Biol. 1995 Jun-Jul;19(6-7):625-8.

PMID:7590030
Abstract

We report a case of hepatic and splenic angiosarcoma in a 34 year-old man presenting with hemoperitoneum and consumption coagulopathy. Histological and immunohistological diagnosis was based on a biopsy specimen obtained through the transjugular route. Embolization via the splenic artery for the most significant lesions and intravenous chemotherapy resulted in a partial response in the liver and splenic tumour masses and survival with a good quality of life. The initial complications recurred after chemotherapy was stopped and death occurred after 15 months. The benefit of arterial embolization and chemotherapy in this rare and usually rapidly fatal disease should be assessed in other patients.

摘要

我们报告了一例34岁男性的肝脾血管肉瘤病例,该患者表现为腹腔积血和消耗性凝血病。组织学和免疫组织学诊断基于经颈静脉途径获取的活检标本。对最显著的病变进行脾动脉栓塞并联合静脉化疗,使肝脏和脾脏肿瘤肿块出现部分缓解,患者存活且生活质量良好。化疗停止后最初的并发症复发,15个月后患者死亡。对于这种罕见且通常迅速致命的疾病,应在其他患者中评估动脉栓塞和化疗的益处。

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