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编码人P5的cDNA的克隆与测序

Cloning and sequencing of the cDNA encoding human P5.

作者信息

Hayano T, Kikuchi M

机构信息

Protein Engineering Research Institute, Osaka, Japan.

出版信息

Gene. 1995 Oct 27;164(2):377-8. doi: 10.1016/0378-1119(95)00474-k.

DOI:10.1016/0378-1119(95)00474-k
PMID:7590364
Abstract

The cDNA encoding human P5 was cloned and sequenced. The predicted 440-amino-acid (aa) sequence of human P5 contains two thioredoxin-like domains, which are also found in members of the protein disulfide isomerase superfamily. The human and hamster P5 genes reveal 87 and 93% similarity in their nucleotide and deduced aa sequences, respectively.

摘要

编码人P5的互补DNA（cDNA）被克隆并测序。预测的人P5的440个氨基酸序列包含两个硫氧还蛋白样结构域，在蛋白质二硫键异构酶超家族成员中也能发现这些结构域。人和仓鼠的P5基因在核苷酸序列和推导的氨基酸序列上分别显示出87%和93%的相似性。

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