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Mapping of the genes for four members of the transmembrane 4 superfamily: mouse Cd9, Cd63, Cd81, and Cd82.

作者信息

Seldin M F, Rochelle J M, Tomlinson M G, Wright M D

机构信息

The MRC Cellular Immunology Unit, Sir William Dunn School of Pathology, South Parks Road, University of Oxford, Oxford OX1 3RE, UK.

出版信息

Immunogenetics. 1995;42(5):422-5. doi: 10.1007/BF00179406.

DOI:10.1007/BF00179406
PMID:7590978
Abstract
摘要

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Mapping of the genes for four members of the transmembrane 4 superfamily: mouse Cd9, Cd63, Cd81, and Cd82.跨膜4超家族四个成员的基因定位：小鼠Cd9、Cd63、Cd81和Cd82
Immunogenetics. 1995;42(5):422-5. doi: 10.1007/BF00179406.
2
Functional analysis of four tetraspans, CD9, CD53, CD81, and CD82, suggests a common role in costimulation, cell adhesion, and migration: only CD9 upregulates HB-EGF activity.对四种四跨膜蛋白CD9、CD53、CD81和CD82的功能分析表明，它们在共刺激、细胞黏附和迁移中具有共同作用：只有CD9能上调肝素结合表皮生长因子（HB-EGF）的活性。
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3
CD63 tetraspanin slows down cell migration and translocates to the endosomal-lysosomal-MIICs route after extracellular stimuli in human immature dendritic cells.在人类未成熟树突状细胞中，细胞外刺激后，四跨膜蛋白CD63会减缓细胞迁移，并转位至内体-溶酶体-MIICs途径。
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CD19 is linked to the integrin-associated tetraspans CD9, CD81, and CD82.CD19与整合素相关的四跨膜蛋白CD9、CD81和CD82相关联。
J Biol Chem. 1998 Nov 13;273(46):30537-43. doi: 10.1074/jbc.273.46.30537.
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Transmembrane 4 superfamily as a prognostic factor in pancreatic cancer.跨膜4超家族作为胰腺癌的一个预后因素
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CD9, CD63, CD81, and CD82 are components of a surface tetraspan network connected to HLA-DR and VLA integrins.CD9、CD63、CD81和CD82是与HLA-DR和VLA整合素相连的表面四跨膜蛋白网络的组成成分。
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Transmembrane-4 superfamily proteins CD81 (TAPA-1), CD82, CD63, and CD53 specifically associated with integrin alpha 4 beta 1 (CD49d/CD29).跨膜4超家族蛋白CD81（TAPA-1）、CD82、CD63和CD53与整合素α4β1（CD49d/CD29）特异性相关。
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Association between the rat homologue of CO-029, a metastasis-associated tetraspanin molecule and consumption coagulopathy.转移相关四跨膜蛋白分子CO-029的大鼠同源物与消耗性凝血病之间的关联
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本文引用的文献

1
Suppression of cell motility and metastasis by transfection with human motility-related protein (MRP-1/CD9) DNA.通过转染人运动相关蛋白（MRP-1/CD9）DNA抑制细胞运动性和转移
J Exp Med. 1993 May 1;177(5):1231-7. doi: 10.1084/jem.177.5.1231.
2
Gene structure, chromosomal localization, and protein sequence of mouse CD53 (Cd53): evidence that the transmembrane 4 superfamily arose by gene duplication.小鼠CD53（Cd53）的基因结构、染色体定位及蛋白质序列：跨膜4超家族由基因复制产生的证据
Int Immunol. 1993 Feb;5(2):209-16. doi: 10.1093/intimm/5.2.209.
3
The genes for CD37, CD53, and R2, all members of a novel gene family, are located on different chromosomes.
新型基因家族的所有成员，即CD37、CD53和R2的基因，位于不同的染色体上。
Immunogenetics. 1993;37(6):461-5. doi: 10.1007/BF00222471.
4
CD53, a protein with four membrane-spanning domains, mediates signal transduction in human monocytes and B cells.CD53是一种具有四个跨膜结构域的蛋白质，可介导人类单核细胞和B细胞中的信号转导。
J Immunol. 1993 Jul 15;151(2):707-16.
5
A glial-specific voltage-sensitive Na channel gene maps close to clustered genes for neuronal isoforms on mouse chromosome 2.一种胶质细胞特异性电压敏感钠通道基因定位于小鼠2号染色体上与神经元亚型的成簇基因相邻的位置。
Biochem Biophys Res Commun. 1993 Nov 30;197(1):100-4. doi: 10.1006/bbrc.1993.2446.
6
Molecular cloning of the mouse equivalent of CD9 antigen.小鼠CD9抗原等同物的分子克隆。
Thromb Res. 1993 Sep 1;71(5):377-83. doi: 10.1016/0049-3848(93)90162-h.
7
Chromosomal localization of three human genes coding for A15, L6, and S5.7 (TAPA1): all members of the transmembrane 4 superfamily of proteins.编码A15、L6和S5.7（TAPA1）的三个人类基因的染色体定位：均为跨膜4蛋白超家族的成员。
Immunogenetics. 1994;39(5):329-34. doi: 10.1007/BF00189229.
8
Molecular cloning of the murine homologue of CD63/ME491 and detection of its strong expression in the kidney and activated macrophages.CD63/ME491小鼠同源物的分子克隆及其在肾脏和活化巨噬细胞中的强表达检测。
Biochim Biophys Acta. 1994 Apr 6;1217(3):312-6. doi: 10.1016/0167-4781(94)90291-7.
9
SAS, a gene amplified in human sarcomas, encodes a new member of the transmembrane 4 superfamily of proteins.SAS是一种在人类肉瘤中扩增的基因，它编码跨膜4蛋白超家族的一个新成员。
Oncogene. 1994 Apr;9(4):1205-11.
10
Mouse homologue of C33 antigen (CD82), a member of the transmembrane 4 superfamily: complementary DNA, genomic structure, and expression.C33抗原（CD82）的小鼠同源物，跨膜4超家族成员：互补DNA、基因组结构及表达
Cell Immunol. 1994 Aug;157(1):144-57. doi: 10.1006/cimm.1994.1212.