跨膜4超家族四个成员的基因定位：小鼠Cd9、Cd63、Cd81和Cd82 - Suppr

Mapping of the genes for four members of the transmembrane 4 superfamily: mouse Cd9, Cd63, Cd81, and Cd82.

作者信息

Seldin M F, Rochelle J M, Tomlinson M G, Wright M D

机构信息

The MRC Cellular Immunology Unit, Sir William Dunn School of Pathology, South Parks Road, University of Oxford, Oxford OX1 3RE, UK.

出版信息

Immunogenetics. 1995;42(5):422-5. doi: 10.1007/BF00179406.

DOI:10.1007/BF00179406

PMID:7590978

Abstract

摘要

相似文献

Mapping of the genes for four members of the transmembrane 4 superfamily: mouse Cd9, Cd63, Cd81, and Cd82.跨膜4超家族四个成员的基因定位：小鼠Cd9、Cd63、Cd81和Cd82

Immunogenetics. 1995;42(5):422-5. doi: 10.1007/BF00179406.

Functional analysis of four tetraspans, CD9, CD53, CD81, and CD82, suggests a common role in costimulation, cell adhesion, and migration: only CD9 upregulates HB-EGF activity.对四种四跨膜蛋白CD9、CD53、CD81和CD82的功能分析表明，它们在共刺激、细胞黏附和迁移中具有共同作用：只有CD9能上调肝素结合表皮生长因子（HB-EGF）的活性。

Cell Immunol. 1997 Dec 15;182(2):105-12. doi: 10.1006/cimm.1997.1223.

CD63 tetraspanin slows down cell migration and translocates to the endosomal-lysosomal-MIICs route after extracellular stimuli in human immature dendritic cells.在人类未成熟树突状细胞中，细胞外刺激后，四跨膜蛋白CD63会减缓细胞迁移，并转位至内体-溶酶体-MIICs途径。

Blood. 2004 Aug 15;104(4):1183-90. doi: 10.1182/blood-2004-01-0104. Epub 2004 May 6.

CD19 is linked to the integrin-associated tetraspans CD9, CD81, and CD82.CD19与整合素相关的四跨膜蛋白CD9、CD81和CD82相关联。

J Biol Chem. 1998 Nov 13;273(46):30537-43. doi: 10.1074/jbc.273.46.30537.

Transmembrane 4 superfamily as a prognostic factor in pancreatic cancer.跨膜4超家族作为胰腺癌的一个预后因素

Int J Cancer. 1998 Oct 23;79(5):509-16. doi: 10.1002/(sici)1097-0215(19981023)79:5<509::aid-ijc11>3.0.co;2-x.

CD9, CD63, CD81, and CD82 are components of a surface tetraspan network connected to HLA-DR and VLA integrins.CD9、CD63、CD81和CD82是与HLA-DR和VLA整合素相连的表面四跨膜蛋白网络的组成成分。

Eur J Immunol. 1996 Nov;26(11):2657-65. doi: 10.1002/eji.1830261117.

Expression of tetraspanin adaptor proteins below defined threshold values is associated with in vitro invasiveness of mammary carcinoma cells.四跨膜蛋白衔接蛋白低于规定阈值的表达与乳腺癌细胞的体外侵袭性相关。

Oncol Rep. 2003 Mar-Apr;10(2):405-10.

Importance of the major extracellular domain of CD9 and the epidermal growth factor (EGF)-like domain of heparin-binding EGF-like growth factor for up-regulation of binding and activity.CD9主要细胞外结构域及肝素结合表皮生长因子样生长因子的表皮生长因子（EGF）样结构域对结合及活性上调的重要性。

J Biol Chem. 2000 Jun 16;275(24):18284-90. doi: 10.1074/jbc.M907971199.

Down-regulation of TM4SF is associated with the metastatic potential of gastric carcinoma TM4SF members in gastric carcinoma.TM4SF 下调与胃癌的转移潜能有关 TM4SF 成员在胃癌中。

World J Surg Oncol. 2011 Apr 27;9:43. doi: 10.1186/1477-7819-9-43.

Transmembrane-4 superfamily proteins CD81 (TAPA-1), CD82, CD63, and CD53 specifically associated with integrin alpha 4 beta 1 (CD49d/CD29).跨膜4超家族蛋白CD81（TAPA-1）、CD82、CD63和CD53与整合素α4β1（CD49d/CD29）特异性相关。

J Immunol. 1996 Sep 1;157(5):2039-47.

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Cocaine-Specific Effects on Exosome Biogenesis in Microglial Cells.可卡因对小胶质细胞外泌体生成的特异性影响。

Neurochem Res. 2021 Apr;46(4):1006-1018. doi: 10.1007/s11064-021-03231-2. Epub 2021 Feb 8.

Association between the rat homologue of CO-029, a metastasis-associated tetraspanin molecule and consumption coagulopathy.转移相关四跨膜蛋白分子CO-029的大鼠同源物与消耗性凝血病之间的关联

J Cell Biol. 1998 Apr 6;141(1):267-80. doi: 10.1083/jcb.141.1.267.

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Suppression of cell motility and metastasis by transfection with human motility-related protein (MRP-1/CD9) DNA.通过转染人运动相关蛋白（MRP-1/CD9）DNA抑制细胞运动性和转移

J Exp Med. 1993 May 1;177(5):1231-7. doi: 10.1084/jem.177.5.1231.

Gene structure, chromosomal localization, and protein sequence of mouse CD53 (Cd53): evidence that the transmembrane 4 superfamily arose by gene duplication.小鼠CD53（Cd53）的基因结构、染色体定位及蛋白质序列：跨膜4超家族由基因复制产生的证据

Int Immunol. 1993 Feb;5(2):209-16. doi: 10.1093/intimm/5.2.209.

The genes for CD37, CD53, and R2, all members of a novel gene family, are located on different chromosomes.新型基因家族的所有成员，即CD37、CD53和R2的基因，位于不同的染色体上。

Immunogenetics. 1993;37(6):461-5. doi: 10.1007/BF00222471.

CD53, a protein with four membrane-spanning domains, mediates signal transduction in human monocytes and B cells.CD53是一种具有四个跨膜结构域的蛋白质，可介导人类单核细胞和B细胞中的信号转导。

J Immunol. 1993 Jul 15;151(2):707-16.

A glial-specific voltage-sensitive Na channel gene maps close to clustered genes for neuronal isoforms on mouse chromosome 2.一种胶质细胞特异性电压敏感钠通道基因定位于小鼠2号染色体上与神经元亚型的成簇基因相邻的位置。

Biochem Biophys Res Commun. 1993 Nov 30;197(1):100-4. doi: 10.1006/bbrc.1993.2446.

Molecular cloning of the mouse equivalent of CD9 antigen.小鼠CD9抗原等同物的分子克隆。

Thromb Res. 1993 Sep 1;71(5):377-83. doi: 10.1016/0049-3848(93)90162-h.

Chromosomal localization of three human genes coding for A15, L6, and S5.7 (TAPA1): all members of the transmembrane 4 superfamily of proteins.编码A15、L6和S5.7（TAPA1）的三个人类基因的染色体定位：均为跨膜4蛋白超家族的成员。

Immunogenetics. 1994;39(5):329-34. doi: 10.1007/BF00189229.

Molecular cloning of the murine homologue of CD63/ME491 and detection of its strong expression in the kidney and activated macrophages.CD63/ME491小鼠同源物的分子克隆及其在肾脏和活化巨噬细胞中的强表达检测。

Biochim Biophys Acta. 1994 Apr 6;1217(3):312-6. doi: 10.1016/0167-4781(94)90291-7.

SAS, a gene amplified in human sarcomas, encodes a new member of the transmembrane 4 superfamily of proteins.SAS是一种在人类肉瘤中扩增的基因，它编码跨膜4蛋白超家族的一个新成员。

Oncogene. 1994 Apr;9(4):1205-11.

Mouse homologue of C33 antigen (CD82), a member of the transmembrane 4 superfamily: complementary DNA, genomic structure, and expression.C33抗原（CD82）的小鼠同源物，跨膜4超家族成员：互补DNA、基因组结构及表达

Cell Immunol. 1994 Aug;157(1):144-57. doi: 10.1006/cimm.1994.1212.

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Mapping of the genes for four members of the transmembrane 4 superfamily: mouse Cd9, Cd63, Cd81, and Cd82.

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