Batterman H J, Peek J A, Loutit J S, Falkow S, Tompkins L S
Department of Medicine, Stanford University, California 94305, USA.
Infect Immun. 1995 Nov;63(11):4553-6. doi: 10.1128/iai.63.11.4553-4556.1995.
Bartonella henselae expresses pili phenotypically similar to type 4 pili. B. henselae pilus expression undergoes phase variation with multiple passages. Low-passage-number, piliated B. henselae adhered to and invaded HEp-2 cells to a greater extent than did multiply passaged B. henselae with reduced pilus expression. Pili may be a pathogenic determinant for Bartonella species.
汉赛巴尔通体表达的菌毛在表型上与4型菌毛相似。汉赛巴尔通体菌毛表达会随着多次传代而发生相变。低传代次数的、有菌毛的汉赛巴尔通体比传代多次且菌毛表达减少的汉赛巴尔通体更能有效地黏附和侵入HEp-2细胞。菌毛可能是巴尔通体属细菌的一个致病决定因素。