Fukuchi N, Furihata K, Nakayama J, Goudo T, Takayama S, Isogai A, Suzuki A
Department of Agricultural Chemistry, University of Tokyo, Japan.
J Antibiot (Tokyo). 1995 Sep;48(9):1004-10. doi: 10.7164/antibiotics.48.1004.
In the course of screening search for plant growth regulators, a culture filtrate of Streptomyces graminofaciens 3C02 was found to inhibit the growth of lettuce seedlings. The active substances, named rotihibin A (1) and B (2), were revealed to be lipo-peptidal compounds. Rotihibins inhibit growth of various plants at below 1 microgram/ml, but do not show lethal activity even at higher doses.