Peters J, Kondo K L, Lee R K, Lin C K, Inderlied C B
Department of Pathology, Childrens Hospital Los Angeles, California, USA.
J Antimicrob Chemother. 1995 May;35(5):675-9. doi: 10.1093/jac/35.5.675.
Options for treating disseminated Mycobacterium avium complex (MAC) disease have improved. However, efficacy is not always certain, resistance is common and rapidly bactericidal agents would improve efficacy and prevent resistance. Certain oxazolidinones were tested against MAC strains and inhibited growth at expected serum concentrations or lower. Activity correlated with hydrophobicity and one agent was bactericidal at concentrations two to five times greater than the MIC.
播散性鸟分枝杆菌复合群（MAC）病的治疗选择有所改善。然而，疗效并不总是确定的，耐药很常见，快速杀菌药物将提高疗效并预防耐药。对某些恶唑烷酮进行了针对MAC菌株的测试，结果显示它们在预期的血清浓度或更低浓度下可抑制生长。活性与疏水性相关，一种药物在浓度比最低抑菌浓度（MIC）高两到五倍时具有杀菌作用。
