比阿培南对964株需氧菌临床分离株的体外活性。
The in-vitro activity of biapanem against 964 clinical isolates of aerobic bacteria.
作者信息
Raymond N J, Bremner D A
机构信息
Department of Microbiology, Middlemore Hospital, Otahuhu, Auckland, New Zealand.
出版信息
J Antimicrob Chemother. 1995 May;35(5):681-6. doi: 10.1093/jac/35.5.681.
PMID:7592182
Abstract
The in-vitro susceptibilities of 964 clinical isolates of aerobic bacteria to biapenem (a novel carbapenem), imipenem, ceftazidime and ciprofloxacin were determined by an agar dilution method. Compared with imipenem, biapenem exhibited greater activity against aerobic Gram-negative bacilli, similar activity against Neisseria meningitidis, Neisseria gonorrhoeae and Haemophilus influenzae and less activity against Gram-positive cocci.
摘要
采用琼脂稀释法测定了964株需氧菌临床分离株对新型碳青霉烯类药物比阿培南、亚胺培南、头孢他啶和环丙沙星的体外敏感性。与亚胺培南相比，比阿培南对需氧革兰氏阴性杆菌表现出更强的活性，对脑膜炎奈瑟菌、淋病奈瑟菌和流感嗜血杆菌表现出相似的活性，而对革兰氏阳性球菌的活性较弱。
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