Pentelényi T, Kammerer L, Stützel M, Balázsi I
Injury. 1979 Feb;10(3):201-8. doi: 10.1016/0020-1383(79)90009-3.
Serial fasting blood glucose and basal serum insulin were measured in brain-injured patients. The endocrine changes were compared with the level of consciousness. Evaluating the serial examinations of 92 brain-injured and 31 control patients we came to the following conclusions. There is a quantitative correlation between the alterations in the level of consciousness and the fasting blood-glucose and serum-insulin levels in brain-injured patients. Deep coma is connected with a high blood-sugar level, clear consciousness with a normal glucose level. The insulin level is, however, decreased in the comatose state and normal in the state of clear consciousness. According to the alterations in blood-glucose and insulin levels, brain-injured patients can be divided into four groups. The alterations in the insulin level cannot give a proper explanation of the blood-sugar changes. Some changes in the levels of both blood glucose and serum insulin may have prognostic significance. According to our results it can be supposed that certain cerebral structures take part in the regulation of the basal insulin secretion.
对脑损伤患者进行了空腹血糖和基础血清胰岛素的系列检测。将内分泌变化与意识水平进行了比较。通过对92例脑损伤患者和31例对照患者的系列检查评估，我们得出以下结论。脑损伤患者意识水平的改变与空腹血糖和血清胰岛素水平之间存在定量相关性。深度昏迷与高血糖水平相关，清醒意识与正常血糖水平相关。然而，胰岛素水平在昏迷状态下降低，在清醒状态下正常。根据血糖和胰岛素水平的变化，脑损伤患者可分为四组。胰岛素水平的变化不能对血糖变化做出恰当解释。血糖和血清胰岛素水平的某些变化可能具有预后意义。根据我们的结果，可以推测某些脑结构参与基础胰岛素分泌的调节。
