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儿童期韦尔斯综合征:病例报告及文献复习

Wells' syndrome in childhood: case report and review of the literature.

作者信息

Anderson C R, Jenkins D, Tron V, Prendiville J S

机构信息

Division of Dermatology, University of British Columbia, Vancouver, Canada.

出版信息

J Am Acad Dermatol. 1995 Nov;33(5 Pt 2):857-64. doi: 10.1016/0190-9622(95)90423-9.

DOI:10.1016/0190-9622(95)90423-9
PMID:7593797
Abstract

We report a severe case of Wells' syndrome, or eosinophilic cellulitis, after a bee sting in a 4-year-old girl. The patient had a widespread, painful, blistering eruption that was subsequently complicated by Pseudomonas aeruginosa superinfection and septicemia, hypoalbuminemia, anemia, and neutropenia. The skin lesions responded to systemic steroid therapy. There was residual scarring alopecia of the scalp. There have been 17 previous reports of childhood Wells' syndrome. We believe that this disorder is a distinct entity that should be considered in the differential diagnosis of blistering diseases in children.

摘要

我们报告了一名4岁女童在被蜜蜂蜇伤后发生严重韦尔斯综合征(即嗜酸性粒细胞性蜂窝织炎)的病例。患者出现广泛、疼痛性水疱性皮疹,随后并发铜绿假单胞菌二重感染及败血症、低白蛋白血症、贫血和中性粒细胞减少症。皮肤病变对全身类固醇治疗有反应。头皮有残留瘢痕性脱发。此前已有17例儿童韦尔斯综合征的报告。我们认为这种疾病是一种独特的病症,在儿童水疱性疾病的鉴别诊断中应予以考虑。

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1
Wells' syndrome in childhood: case report and review of the literature.儿童期韦尔斯综合征:病例报告及文献复习
J Am Acad Dermatol. 1995 Nov;33(5 Pt 2):857-64. doi: 10.1016/0190-9622(95)90423-9.
2
Eosinophilic cellulitis (Wells' syndrome) and an insect bite-like reaction in a patient with non-Hodgkin B cell lymphoma.一名非霍奇金B细胞淋巴瘤患者出现嗜酸性粒细胞性蜂窝织炎(韦尔斯综合征)及类似昆虫叮咬的反应。
Eur J Dermatol. 2011 May-Jun;21(3):422-3. doi: 10.1684/ejd.2011.1296.
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Wells' syndrome, insect bites, and eosinophils.韦尔斯综合征、昆虫叮咬与嗜酸性粒细胞
Dermatol Clin. 1990 Apr;8(2):287-93.
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Wells' syndrome: vesiculobullous presentation and possible role of ectoparasites.韦尔斯综合征:水疱大疱表现及外寄生虫的可能作用。
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Eosinophilic cellulitis (Wells' syndrome): histologic and clinical features in arthropod bite reactions.嗜酸性粒细胞性蜂窝织炎(韦尔斯综合征):节肢动物叮咬反应的组织学和临床特征
J Am Acad Dermatol. 1984 Dec;11(6):1043-9. doi: 10.1016/s0190-9622(84)70257-x.
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Wells' syndrome presenting as a noninfectious bullous cellulitis in a child.以非感染性大疱性蜂窝织炎形式出现的儿童韦尔斯综合征。
Pediatr Dermatol. 2012 Mar-Apr;29(2):224-6. doi: 10.1111/j.1525-1470.2010.01289.x. Epub 2010 Dec 7.
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Bullous "cellulitis" with eosinophilia: case report and review of Wells' syndrome in childhood.伴有嗜酸性粒细胞增多的大疱性“蜂窝织炎”:儿童期韦尔斯综合征病例报告及文献复习
Pediatrics. 2005 Jul;116(1):e149-55. doi: 10.1542/peds.2004-2273.
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Eosinophilic cellulitis after honeybee sting.蜜蜂蜇伤后嗜酸性粒细胞性蜂窝织炎
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[Multilocular painful urticarial plaques. Eosinophilic cellulitis (Wells syndrome)].[多房性疼痛性荨麻疹斑块。嗜酸性粒细胞性蜂窝织炎(韦尔斯综合征)]
Praxis (Bern 1994). 2004 Oct 27;93(44):1831-5. doi: 10.1024/0369-8394.93.44.1831.
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[A case of eosinophilic cellulitis (Wells' syndrome)].[嗜酸性粒细胞性蜂窝织炎(韦尔斯综合征)一例]
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Eosinophilic cellulitis or Wells' syndrome in a 6-year-old child.一名6岁儿童患嗜酸性粒细胞性蜂窝织炎或威尔斯综合征。
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