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先天性鱼鳞病患者皮肤癌发病率增加。

Increased incidence of cutaneous carcinomas in patients with congenital ichthyosis.

作者信息

Elbaum D J, Kurz G, MacDuff M

机构信息

Kern Dermatology Medical Group, Inc., Bakersfield, CA, USA.

出版信息

J Am Acad Dermatol. 1995 Nov;33(5 Pt 2):884-6. doi: 10.1016/0190-9622(95)90428-x.

DOI:10.1016/0190-9622(95)90428-x
PMID:7593802
Abstract

It is well known that patients with heritable cutaneous diseases may have excess tumors during their lifetime. This relationship has been shown for such diverse conditions as xeroderma pigmentosum, Bloom syndrome, basal cell nevus syndrome, and psoriasis. However, multiple cutaneous tumors have not been previously described in people with lamellar ichthyosis. This article describes the cases of two such patients, possible treatment, and a previously undescribed ichthyosis syndrome.

摘要

众所周知,患有遗传性皮肤病的患者一生中可能会有过多的肿瘤。这种关系在诸如着色性干皮病、布卢姆综合征、基底细胞痣综合征和银屑病等多种病症中都有体现。然而,此前尚未有关于板层状鱼鳞病患者出现多发性皮肤肿瘤的描述。本文介绍了两名此类患者的病例、可能的治疗方法以及一种此前未被描述过的鱼鳞病综合征。

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Increased incidence of cutaneous carcinomas in patients with congenital ichthyosis.先天性鱼鳞病患者皮肤癌发病率增加。
J Am Acad Dermatol. 1995 Nov;33(5 Pt 2):884-6. doi: 10.1016/0190-9622(95)90428-x.
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Xeroderma pigmentosum, malignant melanoma, and congenital ichthyosis. A family study.着色性干皮病、恶性黑色素瘤和先天性鱼鳞病。一项家族研究。
Arch Dermatol. 1967 Dec;96(6):625-35.
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Keratitis, ichthyosis, and deafness (KID) syndrome. Vertical transmission and death from multiple squamous cell carcinomas.角膜炎、鱼鳞病和耳聋(KID)综合征。垂直传播及死于多发性鳞状细胞癌。
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NMSC in organ transplant recipients and other high-risk groups.器官移植受者及其他高危人群中的非黑色素瘤皮肤癌
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Squamous cell carcinoma arising from Keratitis-ichthyosis-deafness syndrome.由角膜炎-鱼鳞病-耳聋综合征引发的鳞状细胞癌。
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[A case of squamous cell carcinoma of the hard palate in a patient with basal cell nevus syndrome].[基底细胞痣综合征患者硬腭鳞状细胞癌1例]
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Arginine- but not alanine-rich carboxy-termini trigger nuclear translocation of mutant keratin 10 in ichthyosis with confetti.富含精氨酸但不含丙氨酸的角蛋白 10 羧基末端触发鱼鳞癣的核易位。
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Congenital ichthyosis patient with squamous cell carcinoma of the skin who received concurrent chemoradiation: A case report.
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Adv Radiat Oncol. 2017 Sep 25;3(1):76-80. doi: 10.1016/j.adro.2017.09.006. eCollection 2018 Jan-Mar.
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Ichthyosis with confetti: clinics, molecular genetics and management.点状鱼鳞病:临床、分子遗传学与管理
Orphanet J Rare Dis. 2015 Sep 17;10:115. doi: 10.1186/s13023-015-0336-4.
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A case of lamellar ichthyosis with rickets and carcinoma of the hypopharynx.一例板层状鱼鳞病合并佝偻病及下咽癌。
Indian J Dermatol. 2014 Nov;59(6):634. doi: 10.4103/0019-5154.143585.
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Phenotypic expansion in ichthyosis with confetti.带有五彩纸屑样改变的鱼鳞病中的表型扩展
JAMA Dermatol. 2015 Jan;151(1):15-6. doi: 10.1001/jamadermatol.2014.2525.
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