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院外心脏骤停后昏迷患者的早期颈静脉球部氧合监测

Early jugular bulb oxygenation monitoring in comatose patients after an out-of-hospital cardiac arrest.

作者信息

van der Hoeven J G, de Koning J, Compier E A, Meinders A E

机构信息

Department of General Internal Medicine, University Hospital Leiden, The Netherlands.

出版信息

Intensive Care Med. 1995 Jul;21(7):567-72. doi: 10.1007/BF01700161.

Abstract

OBJECTIVE

To determine the role of early jugular bulb oxygenation monitoring in comatose patients after cardiac arrest.

DESIGN

Prospective sequential study.

SETTING

Medical intensive care unit in a university hospital.

PATIENTS

Thirteen patients comatose after out-of-hospital cardiac arrest.

INTERVENTIONS

A standard hemodynamic protocol.

MEASUREMENTS AND RESULTS

Jugular bulb oxygen saturation levels and oxygen extraction ratios could not discriminate between patients with good (6) and poor (7) cerebral outcome. This was also true for the jugular bulb-arterial lactate difference. Survivors had significantly higher overall oxygen transport values than non-survivors.

CONCLUSIONS

Jugular bulb oxygenation monitoring during the first few hours after cardiac arrest cannot reliably discriminate between comatose patients with a good and poor cerebral outcome. Further studies with an extended monitoring period are thus required.

摘要

目的

确定早期颈静脉球部氧合监测在心脏骤停后昏迷患者中的作用。

设计

前瞻性序列研究。

地点

一所大学医院的医学重症监护病房。

患者

13例院外心脏骤停后昏迷的患者。

干预措施

标准血流动力学方案。

测量与结果

颈静脉球部氧饱和度水平和氧摄取率无法区分脑功能预后良好(6例)和预后不良(7例)的患者。颈静脉球部-动脉血乳酸差值情况亦是如此。幸存者的总体氧输送值显著高于非幸存者。

结论

心脏骤停后头几个小时内的颈静脉球部氧合监测无法可靠地区分脑功能预后良好和预后不良的昏迷患者。因此,需要进行更长监测期的进一步研究。

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