O'Murchu B, Foreman R D, Shaw R E, Brown D L, Peterson K L, Buchbinder M
Division of Cardiology, University of California San Diego Medical Center, California, USA.
J Am Coll Cardiol. 1995 Nov 1;26(5):1270-5. doi: 10.1016/0735-1097(96)81473-2.
This study sought to evaluate the role of intraaortic balloon pump counterpulsation in preventing hemodynamic instability and promoting a successful outcome during percutaneous transluminal coronary rotational atherectomy in high risk patients.
The application of rotational atherectomy has widened to include patients with complex lesions and left ventricular dysfunction. Although intraaortic balloon pumping has been successfully used to provide hemodynamic support during balloon angioplasty, its role in high risk rotational atherectomy has not yet been defined.
In a retrospective review of 159 consecutive high risk patients who underwent rotational atherectomy, 28 had an intraaortic balloon pump placed electively before the procedure (Group 1) whereas 131 did not (Group 2).
Group 1 was older and more likely to have multivessel disease and left ventricular dysfunction. Augmented diastolic pressure was maintained > 90 mm Hg in all Group 1 patients, and significant procedure-related hypotension was encountered in nine Group 2 patients, requiring an emergency intraaortic balloon pump in five. Procedural success was achieved in all 28 patients in Group 1 and in 118 in Group 2 (p = 0.07). Slow flow occurred in 18% and 17% of Group 1 and 2 patients, respectively. Among patients with slow flow, non-Q wave myocardial infarction occurred only in Group 2 (0% vs. 27%). On multivariate analysis, elective intraaortic balloon pump placement was the only variable to correlate with a successful procedure uncomplicated by hypotension (p < 0.05). Hospital stay and vascular complications were similar in both groups.
Elective placement of an intraaortic balloon pump before coronary rotational atherectomy in selected high risk patients promotes both procedural hemodynamic stability and a successful outcome.
本研究旨在评估主动脉内球囊反搏在高危患者经皮腔内冠状动脉旋磨术期间预防血流动力学不稳定及促进手术成功结局方面的作用。
旋磨术的应用范围已扩大至包括有复杂病变和左心室功能障碍的患者。尽管主动脉内球囊泵已成功用于在球囊血管成形术期间提供血流动力学支持,但其在高危旋磨术中的作用尚未明确。
在一项对159例连续接受旋磨术的高危患者的回顾性研究中,28例在手术前选择性地置入了主动脉内球囊泵(第1组),而131例未置入(第2组)。
第1组患者年龄更大,更可能患有多支血管病变和左心室功能障碍。第1组所有患者的舒张期增压均维持>90 mmHg,第2组有9例患者出现了与手术相关的显著低血压,其中5例需要紧急置入主动脉内球囊泵。第1组的所有28例患者和第2组的118例患者手术成功(p = 0.07)。第1组和第2组分别有18%和17%的患者出现慢血流。在出现慢血流的患者中,非Q波心肌梗死仅发生在第2组(0%对27%)。多因素分析显示,选择性置入主动脉内球囊泵是与无低血压并发症的成功手术相关的唯一变量(p < 0.05)。两组患者的住院时间和血管并发症相似。
在选定的高危患者中,冠状动脉旋磨术前选择性置入主动脉内球囊泵可促进手术期间的血流动力学稳定及成功结局。