Gerin W, Pickering T G
Hypertension Center/Starr Pavilion ST405, Cornell University Medical College/New York Hospital, NY 10021, USA.
J Hypertens. 1995 Jun;13(6):603-10. doi: 10.1097/00004872-199506000-00005.
To assess the influence of sex, race and parental history of hypertension on blood pressure and heart rate elevations during a stressor, and on the recovery of prestress baseline levels for these parameters.
Five hundred and thirty-seven university undergraduates underwent cardiovascular reactivity testing. A serial-subtraction task served as the stressor. Reactivity was assessed as the difference between baseline and during-task levels, and recovery as the difference between baseline and post-stress levels.
The influence of sex, race and parental history of hypertension on reactivity and recovery was assessed, using analysis of variance models.
No differences were found in reactivity for any of the factors. For recovery, a significant effect was found for parental history of hypertension on systolic blood pressure and a marginal effect on diastolic blood pressure. Post hoc tests revealed that values in groups with two hypertensive parents remained elevated at a significantly higher level than in offspring with either no or one hypertensive parent.
Parental history of hypertension may affect the duration of the blood pressure response to an acute stressor more than the magnitude of the response.
评估性别、种族以及父母的高血压病史对在应激源作用期间血压和心率升高的影响，以及对这些参数恢复到应激前基线水平的影响。
537名大学本科生接受了心血管反应性测试。一个连续减法任务作为应激源。反应性被评估为基线水平与任务期间水平之间的差异，恢复情况被评估为基线水平与应激后水平之间的差异。
使用方差分析模型评估性别、种族以及父母的高血压病史对反应性和恢复情况的影响。
在反应性方面，未发现任何因素存在差异。对于恢复情况，发现父母的高血压病史对收缩压有显著影响，对舒张压有边缘效应。事后检验显示，有两位高血压父母的组中的数值保持在显著高于没有或只有一位高血压父母的后代的水平。
父母的高血压病史可能对急性应激源引起的血压反应的持续时间影响更大，而不是对反应的幅度影响更大。
