Kao S Y, Pong B Y, Li W Y, Gallagher G T, Chang R C
Department of Dentistry, Oral and Maxillofacial Surgery, Veterans General Hospital-Taipei, Taiwan.
Int J Oral Maxillofac Surg. 1995 Jun;24(3):229-32. doi: 10.1016/s0901-5027(06)80134-7.
We present a case of odontogenic carcinoma with ghost-cell keratinization of the right maxilla, with a history of 23 years after initial treatment. Within this period, multiple local recurrence, as well as metastasis to axilla, brain, and lung, was noted. Several attempts at resection of the primary lesion were unsuccessful at achieving local control, even when supplemented with chemotherapy and radiotherapy. Metastatic tumors were studied histologically, and their morphology coincided with that of the primary tumor. The medical history of the patient and pathologic findings of the tumor are reviewed.
我们报告一例右上颌骨牙源性癌伴影细胞角化,初始治疗后已有23年病史。在此期间,观察到多次局部复发以及腋窝、脑和肺转移。多次尝试切除原发灶均未能实现局部控制,即便辅以化疗和放疗。对转移瘤进行了组织学研究,其形态与原发肿瘤一致。本文回顾了患者的病史及肿瘤的病理检查结果。