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遗传性肌营养不良小鼠(C57 BL/64J/dy品系)的红细胞影(Na+ + K+)ATP酶活性

Erythrocyte ghost (Na+ + K+) ATPase activity in mice with hereditary muscular dystrophy (strain C57 BL/64J/dy).

作者信息

Souweine G, Rolland M O, Maire I, Donas M C

出版信息

J Neurol. 1978 Feb 14;217(3):183-9. doi: 10.1007/BF00312959.

Abstract

Erythrocyte ghost (Na+ + K+) ATPase activity was studied in mice with hereditary muscular dystrophy (strain C 57 BL 6J/dy) and appropriate controls. No difference was observed in the enzymatic activity between dystrophic and any of the healthy genotypes. Ouabain 5 mM and 0.1 mM inhibited the enzymatic activity and no difference was observed between dystrophic and control animals. The results are discussed in the light of the literature.

摘要

对患有遗传性肌营养不良(C 57 BL 6J/dy品系)的小鼠及相应对照小鼠的红细胞血影(Na+ + K+)ATP酶活性进行了研究。在营养不良小鼠和任何健康基因型小鼠之间未观察到酶活性的差异。5 mM和0.1 mM的哇巴因抑制了酶活性,在营养不良小鼠和对照动物之间未观察到差异。结合文献对结果进行了讨论。

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