Bikour M H, Frost E H, Deslandes S, Talbot B, Elazhary Y
Section de virologie, Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec, Canada.
J Gen Virol. 1995 Oct;76 ( Pt 10):2539-47. doi: 10.1099/0022-1317-76-10-2539.
Two antigenically distinct H1N1 influenza A viruses were isolated during an outbreak of respiratory disease in Quebec swine in 1990/91. Analysis of haemagglutinin and partial nucleoprotein sequences indicated that one was a variant of the swine H1N1 influenza virus circulating in the American Midwest whereas the other was very similar to virus isolated from swine in 1930. The existence of this latter isolate supports the concept that influenza viruses can be maintained for long periods in swine, perhaps in geographically limited pockets. Serological evidence indicates that these distinct strains continued to circulate widely in south-central Quebec until at least 1993.
1990/91年魁北克猪群发生呼吸道疾病疫情期间，分离出两种抗原性不同的甲型H1N1流感病毒。对血凝素和部分核蛋白序列的分析表明，一种是在美国中西部流行的猪H1N1流感病毒的变种，而另一种与1930年从猪身上分离出的病毒非常相似。后一种分离株的存在支持了流感病毒可以在猪群中长期存在的观点，可能存在于地理上有限的区域。血清学证据表明，这些不同的毒株至少在1993年之前一直在魁北克中南部广泛传播。
