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埃塞俄比亚阿拉伯按蚊中滴滴涕抗性与倒位多态性的关联检测。

Test for association of DDT resistance with inversion polymorphism in Anopheles arabiensis from Ethiopia.

作者信息

Nigatu W, Curtis C F, Lulu M

机构信息

National Research Institute of Health, Addis Ababa, Ethiopia.

出版信息

J Am Mosq Control Assoc. 1995 Jun;11(2 Pt 1):238-40.

PMID:7595453
Abstract

Association of DDT resistance levels with chromosome inversion polymorphism was investigated in Anopheles arabiensis samples collected from southwestern Ethiopia. The frequencies of the 2Ra, 2Rd, and 3Ra inversions in 1988 and 1990 between the DDT survivors pooled from the 3 times of exposure and unexposed controls did not differ significantly. However, for 2Rb a significant association was observed (Mantel-Haenszel chi 2, stratified for year of collection = 10.4, P < 0.001). The inversion frequency was 56% among unexposed individuals, but it was 64-92% among those surviving exposure.

摘要

在从埃塞俄比亚西南部采集的阿拉伯按蚊样本中,研究了滴滴涕抗性水平与染色体倒位多态性之间的关联。1988年和1990年,在3次暴露后收集的滴滴涕存活者与未暴露对照之间,2Ra、2Rd和3Ra倒位的频率没有显著差异。然而,对于2Rb,观察到显著关联(Mantel-Haenszel卡方检验,按采集年份分层=10.4,P<0.001)。未暴露个体中的倒位频率为56%,但在暴露后存活的个体中为64%-92%。

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