Okamura T, Kawabe J, Kobashi T, Hosokawa C, Shimonishi Y, Ochi H, Wada S, Iwata H
Division of Nuclear Medicine, Osaka City University Medical School.
Kaku Igaku. 1995 May;32(5):495-9.
Yolk sac tumor is one of the histological types of germ cell tumors. Primary retroperitoneal germ cell tumors are extremely rare neoplasms. We report a case of peritoneal metastasis after resection of a primary retroperitoneal germ cell tumor. The peritoneal metastases were detected by 67Ga-scan when CT did not suggest metastatic lesions while the level of alphafetoprotein was still elevated. The 67Ga-scan showed multiple hot spots in the abdomen and pelvis 72 hours after intravenous injection of the tracer and no changes were observed in serial scan taken 6 hours after the first scan. These findings were strongly suggested the dissemination of the malignant tumors. A PET study with 18F-fluorodeoxyglucose was performed and showed extensive uptake in the intraabdominal and intrapelvic cavity. It was also useful for understanding the extension and distribution of the peritoneal metastatic lesions. The sites of the accumulation of 18F-fluorodeoxyglucose corresponded to the results found in postmortem.
卵黄囊瘤是生殖细胞肿瘤的组织学类型之一。原发性腹膜后生殖细胞肿瘤是极其罕见的肿瘤。我们报告一例原发性腹膜后生殖细胞肿瘤切除术后发生腹膜转移的病例。当CT未提示转移病灶而甲胎蛋白水平仍升高时，通过镓-67扫描检测到腹膜转移。静脉注射示踪剂72小时后，镓-67扫描显示腹部和盆腔有多个热点，首次扫描6小时后进行的系列扫描未观察到变化。这些发现强烈提示恶性肿瘤的播散。进行了一项18F-氟脱氧葡萄糖PET研究，结果显示腹盆腔内有广泛摄取。它也有助于了解腹膜转移病灶的范围和分布。18F-氟脱氧葡萄糖的积聚部位与尸检结果相符。
