Su C, Chen B, Wang S, Liu Z
Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, People's Republic of China.
Mutat Res. 1995 Jun;347(1):17-9. doi: 10.1016/0165-7992(95)90027-6.
Dopamine hydrochloride is reported to be a new mutagen precursor in this study. After treatment with nitrite under acidic conditions, dopamine hydrochloride showed direct-acting mutagenicity on Salmonella typhimurium TA100, TA98 and Escherichia coli WP2uvra. The addition of S9 mix did not affect the mutagenicity of nitrosated dopamine significantly in these three strains. Meanwhile, a comparison of the mutagenicity of nitrosated dopamine with nitrosated tyramine was carried out.
