Michałowska-Wender G, Losy J, Wender M
Kliniki Neurologii AM w Poznaniu.
Neurol Neurochir Pol. 1995 Jan-Feb;29(1):33-8.
In 136 clinically definite MS cases the comparison was performed of intrathecal IgG production and detection of oligoclonal bands, evaluated by immunological methods with results of colloidal tests. The obtained results show, that the left side precipitation in colloidal tests indicates the presence of intrathecal IgG production, what was a definite value in the diagnosis of MS. However, the value of colloidal tests is very much limited by several times lower sensitivity of colloidal tests in detection of intrathecal IgG production in comparisons with the evaluation of intrathecal production and detection of oligoclonal bands by the immunological methods.
在136例临床确诊的多发性硬化症(MS)病例中,对鞘内IgG产生情况与寡克隆带检测结果进行了比较,这些检测通过免疫学方法评估,并与胶体试验结果进行对照。所得结果表明,胶体试验中的左侧沉淀表明存在鞘内IgG产生,这在MS诊断中是一个明确的指标。然而,与通过免疫学方法评估鞘内产生及检测寡克隆带相比,胶体试验在检测鞘内IgG产生方面的灵敏度要低几倍,这极大地限制了胶体试验的价值。