Słomko Z, Stasiak A, Drews K
Instytut Ginekologii i Połoznictwa Akademii Medycznej w Poznaniu.
Przegl Epidemiol. 1994;48(4):369-76.
On the ground of contemporary medical literature and our own observations, we have tried to estimate the participation of microorganism infection in preterm labor. In this article, we present mechanism, currently recognized as the most probable, that are leading to preterm labor under condition of perinatal infections. One of them seems to be the production of enzymes by pathological strains. Those enzymes are considered to stimulate decidual and amniotic cells to arachidonic acid metabolism and prostaglandins synthesis. Coexisted with chorionamnionitis the migration of leukocytes that are able to induce prostaglandins synthesis releasing interleukin, can also be an important factor of preterm labor.
基于当代医学文献和我们自己的观察，我们试图评估微生物感染在早产中的作用。在本文中，我们提出了目前被认为最有可能的、在围产期感染情况下导致早产的机制。其中之一似乎是病原菌产生的酶。这些酶被认为能刺激蜕膜细胞和羊膜细胞进行花生四烯酸代谢和前列腺素合成。与绒毛膜羊膜炎并存的、能够通过释放白细胞介素诱导前列腺素合成的白细胞迁移，也可能是早产的一个重要因素。
