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[年轻女性风疹抗体的发生率及风疹疫苗接种结果]

[Incidence of rubella antibodies and the results of vaccination against rubella in young women].

作者信息

Kopeć J, Zgórniak-Nowosielska I

机构信息

Zakład Wirusologii Instytutu Mikrobiologii Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie.

出版信息

Przegl Epidemiol. 1994;48(4):475-9.

PMID:7597186
Abstract

The incidence and the titer of rubella virus antibodies in sera of 936 girls (average age 21 year) from 5 medical school were examined. The antibodies were determined in HI test (Rubenosticon, Organon Teknika). Serum samples were collected in the period of I.1990-IX.1994, and the antibody titer > or = 1:16 was accepted as positive. In 80.3 percent of the examined girls antibodies were found. The mean titer was 1:34.5. Out of 184 seronegative girls, 95 were immunized with Rudivax vaccine. Seroconversion occurred in all, but one person, the mean titer of antibodies was 1:54.6. In 2 vaccinated girls only mild side-effect after immunization occurred.

摘要

对来自5所医学院的936名女生(平均年龄21岁)血清中的风疹病毒抗体发生率和滴度进行了检测。采用血凝抑制试验(Rubenosticon,Organon Teknika)测定抗体。血清样本于1990年1月至1994年9月期间采集,抗体滴度≥1:16被视为阳性。在80.3%的受检女生中发现了抗体。平均滴度为1:34.5。在184名血清阴性的女生中,95人接种了鲁迪瓦克斯疫苗。除一人外,所有人都发生了血清转化,抗体平均滴度为1:54.6。在2名接种疫苗的女生中,仅出现了轻微的免疫后副作用。

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