Garnier P, Michel D, Antoine J C, Solvet P, Gain P, Barral F G, Comtet C
Service de Neurologie, Hôpital de Bellevue, Saint-Etienne.
Rev Neurol (Paris). 1994 Nov;150(11):776-84.
A cohort of 8 patients with myxoma of the left atria and neurological manifestations is reported. Cerebral ischaemia, sometimes responsible for epileptic seizures, led to the discover of the myxoma (5 cases) or recurrence after exeresis (1 case) with imaging evidence of cerebral infarction in 5 cases. The first manifestation was a retinal embolism and temporary ischaemia in 1 case and pulmonary embolism with regressive cerebral ischaemia in another case with bilateral myxoma. Some clinical particularities should be underlined including exercise-induced neurological defect (3 cases), systemic embolism associated with cerebral infarction (3 cases), migraine headache as the initial manifestation (1 case) preceding by a pseudolupic syndrome suggesting the possibility of cerebral vasculitis or infectious endocarditis (1 case). The prognosis depends on the risk of recurrent atrial tumour formation (1 case). Metastases are rare. Multiple cerebral aneurysms (3 cases) did not lead to haemorrhagic complications.
报告了一组8例患有左心房黏液瘤并伴有神经症状的患者。脑缺血有时会引发癫痫发作，导致黏液瘤的发现（5例）或切除术后复发（1例），5例有脑梗死的影像学证据。首发表现为1例视网膜栓塞和短暂性缺血，另1例双侧黏液瘤患者表现为肺栓塞伴进行性脑缺血。应强调一些临床特点，包括运动诱发的神经功能缺损（3例）、与脑梗死相关的全身栓塞（3例）、以偏头痛为首发表现（1例），之前有假狼疮综合征提示可能存在脑血管炎或感染性心内膜炎（1例）。预后取决于心房肿瘤复发的风险（1例）。转移罕见。多发性脑动脉瘤（3例）未导致出血并发症。
