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Hydroxyurea with continuous infusion paclitaxel, 5-fluorouracil, and concomitant radiotherapy for poor-prognosis head and neck cancer.

作者信息

Vokes E E, Stupp R, Haraf D, Moran W, Malone D, Wenig B, Sweeney P, Weichselbaum R R

机构信息

Department of Medicine, University of Chicago, IL, USA.

出版信息

Semin Oncol. 1995 Jun;22(3 Suppl 6):47-52.

PMID:7597433
Abstract

Concomitant chemoradiotherapy holds promise in the therapy of advanced head and neck cancer. We have previously reported on the combination of 5-fluorouracil, hydroxyurea, and concomitant chemoradiotherapy administered on an alternate-week basis. In this ongoing study, we are testing the feasibility of adding continuous-infusion paclitaxel (Taxol; Bristol-Myers Squibb Company, Princeton, NJ) to this combination. Background information and early clinical data are presented.

摘要

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