Varvares M A, Montgomery W W, Hillman R E
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard School of Medicine, Boston, USA.
Ann Otol Rhinol Laryngol. 1995 Jul;104(7):511-5. doi: 10.1177/000348949510400702.
Intralaryngeal Teflon injection for correction of unilateral vocal cord paralysis is known to produce a foreign body giant cell reaction. In our practice, we have seen increasing numbers of patients who had developed dysphonia related to Teflon injection. This patient series was reviewed, as were the surgical technique to correct this condition, voice results, and acoustic analysis of a subset of the patient series. We conclude that dysphonia, secondary to Teflon injection, can be either from overinjection of Teflon or inappropriate injection, or from the proliferative granulomatous response of the larynx to the Teflon. Our technique of laser incision into the superior aspect of the Teflon implant, followed by vaporization and preservation of a margin of mucosa of the cord medially, resulted in improved voice in 8 of 11 patients treated in this manner. Acoustic and aerodynamic analyses reveal significant deficits in vocal function that may persist after procedures used to correct this condition.
喉内注射特氟龙用于纠正单侧声带麻痹会产生异物巨细胞反应。在我们的临床实践中，我们发现越来越多的患者出现了与特氟龙注射相关的发音障碍。我们回顾了这个患者系列，以及纠正这种情况的手术技术、语音结果，还有该患者系列中一部分患者的声学分析。我们得出结论，特氟龙注射继发的发音障碍可能是由于特氟龙注射过量或注射不当，或者是由于喉部对特氟龙的增殖性肉芽肿反应。我们的技术是对特氟龙植入物的上表面进行激光切开，随后汽化并在内侧保留声带黏膜边缘，11例接受这种治疗方式的患者中有8例语音得到改善。声学和空气动力学分析显示，在用于纠正这种情况的手术后，发声功能可能仍存在显著缺陷。
