Sato K, Hirano M
Department of Otolaryngology-Head and Neck Surgery, Kurume University, School of Medicine, Japan.
Ann Otol Rhinol Laryngol. 1995 Jul;104(7):556-62. doi: 10.1177/000348949510400710.
This investigation was carried out to determine the histologic structure of the maculae flavae of human newborn vocal folds. Light microscopic and transmission electron microscopic observations were made with excised human newborn larynges. The results are summarized as follows. 1) Immature maculae flavae were present at the anterior and posterior ends of the bilateral vocal folds. 2) They were round in shape and about 1 x 1 x 1 mm in size. 3) The maculae flavae were composed of fibroblasts, elastic and collagenous fibers, and ground substance. 4) The fibroblast density was great. 5) In newborn maculae flavae, fibroblasts actively started to form elastic and collagenous fibers. 6) The macula flava of the newborn appears to be an important structure in the growth and development of the vocal ligament.
本研究旨在确定人类新生儿声带黄斑的组织学结构。对切除的人类新生儿喉部进行了光镜和透射电镜观察。结果总结如下：1）双侧声带的前端和后端存在未成熟的黄斑。2）它们呈圆形，大小约为1×1×1毫米。3）黄斑由成纤维细胞、弹性纤维和胶原纤维以及基质组成。4）成纤维细胞密度很高。5）在新生儿黄斑中，成纤维细胞积极开始形成弹性纤维和胶原纤维。6）新生儿的黄斑似乎是声带韧带生长发育中的一个重要结构。
