Sato K, Kashiwagi S, Hirano M
Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine.
Nihon Jibiinkoka Gakkai Kaiho. 1997 May;100(5):479-83. doi: 10.3950/jibiinkoka.100.479.
This study was carried out to determine the ultrastructure of the mucous membrane of vocal folds of human newborns. Excised larynges of newborns were observed with a transmission electron microscope. The results obtained are summarized as follows: 1) The epithelium of the edge of the vocal folds consisted of stratified squamous epithelium. It was thin but numerous desmosomes showed firm attachment between cells. 2) The basement membrane zone had the same structure as that of adults. 3) The lamina propria of the vocal fold mucosa was loose in structure and there was no vocal ligament. 4) Fibroblasts were sparse and in the resting phase. 5) Collagenous and elastic fibers were sparse in the lamina propria. Structures of the the collagenous fibers wee mature but those of elastic fibers, were immature morphologically. 6) Ground substance was abundant in the lamina propria. 7) The newborn vocal fold mucosa lacked not only a vocal ligament but also adequate viscoelasticity for vibration.
本研究旨在确定人类新生儿声带黏膜的超微结构。用透射电子显微镜观察新生儿切除的喉部。所得结果总结如下:1)声带边缘的上皮为复层鳞状上皮。它很薄,但大量桥粒显示细胞间附着牢固。2)基底膜区结构与成人相同。3)声带黏膜的固有层结构疏松,无声带韧带。4)成纤维细胞稀疏且处于静止期。5)固有层中胶原纤维和弹性纤维稀疏。胶原纤维结构成熟,但弹性纤维在形态上不成熟。6)固有层中基质丰富。7)新生儿声带黏膜不仅缺乏声带韧带,而且缺乏足够的黏弹性用于振动。