Melia J, Frost T, Graham-Brown R, Hunter J, Marsden A, du Vivier A, Warin A P, White J, Whitehead S, Wroughton M
Cancer Screening Evaluation Unit, Institute of Cancer Research, Sutton, Surrey, UK.
Br J Cancer. 1995 Jul;72(1):224-8. doi: 10.1038/bjc.1995.307.
The aim of the study was to assess the completeness and accuracy of cancer registration for cutaneous malignant melanoma. The study was conducted in seven health districts in England and one health board in Scotland from 1987 to 1989 with a total resident population of 3.6 million. Records from pigmented lesion clinics and pathology laboratories collected during the Cancer Research Campaign's health education programme to promote the early detection of melanoma were matched with cancer registrations from a total of five regional cancer registries. In England 74% out of a total of 642 cases of invasive malignant melanomas (ICD 172) and 44% out of a total of 155 in situ melanomas (ICD 232) had been registered compared with 96% and 100% respectively in Scotland. A significantly higher proportion of late-stage cases was found among registered than among non-registered cases in England (P < 0.001). In all registries the majority of superficial spreading in situ melanomas were miscoded as invasive cases. The annual incidence of invasive malignant melanoma in the English study areas was found to be seven per 100,000 in men and 11 per 100,000 in women, similar to that reported in Scotland. The registries are best at recording thick or late-stage melanomas. As the skin cancer target for Health of the Nation depends on monitoring trends in the incidence of malignant melanoma, future improved ascertainment of cases and changes in the type of cases being registered must be taken into account.
该研究的目的是评估皮肤恶性黑色素瘤癌症登记的完整性和准确性。1987年至1989年期间，在英格兰的七个卫生区和苏格兰的一个卫生委员会开展了此项研究，总人口为360万。在癌症研究运动的健康教育项目（旨在促进黑色素瘤的早期检测）期间收集的色素沉着病变诊所和病理实验室的记录，与来自五个区域癌症登记处的癌症登记信息进行了匹配。在英格兰，642例浸润性恶性黑色素瘤（国际疾病分类代码172）中，有74%已登记，155例原位黑色素瘤（国际疾病分类代码232）中，有44%已登记，而在苏格兰，这两个比例分别为96%和100%。在英格兰，登记病例中的晚期病例比例明显高于未登记病例（P<0.001）。在所有登记处，大多数浅表扩散原位黑色素瘤被错误编码为浸润性病例。在英格兰的研究区域，浸润性恶性黑色素瘤的年发病率为男性每10万人中有7例，女性每10万人中有11例，与苏格兰报告的发病率相似。登记处最擅长记录厚皮或晚期黑色素瘤。由于《国家健康》的皮肤癌目标取决于监测恶性黑色素瘤发病率的趋势，因此必须考虑未来病例确定的改善以及登记病例类型的变化。
