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YNZ22(D17S5)可变数目串联重复多态性在西班牙加泰罗尼亚人群法医学调查中的适用性

Suitability of the YNZ22 (D17S5) VNTR polymorphism for legal medicine investigations in the population of Catalonia (Spain).

作者信息

Gené M, Huguet E, Sánchez-García C, Moreno P, Corbella J, Mezquita J

机构信息

Department of Legal Medicine, Faculty of Medicine, University of Barcelona, Spain.

出版信息

Int J Legal Med. 1995;107(4):222-4. doi: 10.1007/BF01428412.

Abstract

Allele and phenotype frequencies for the YNZ22 locus were determined in a population sample from Catalonia (Spain) using the polymerase chain reaction (PCR). In 311 unrelated individuals, 14 alleles and 56 phenotypes were observed. No deviation from Hardy-Weinberg equilibrium was found. The observed heterozygosity was 81.35%. The YNZ22 polymorphism is useful for paternity testing with a CE value of 70% and an Essen-Möller value of 9.35 (log.).

摘要

采用聚合酶链反应(PCR)测定了来自西班牙加泰罗尼亚人群样本中YNZ22基因座的等位基因和表型频率。在311名无关个体中,观察到14个等位基因和56种表型。未发现偏离哈迪-温伯格平衡的情况。观察到的杂合度为81.35%。YNZ22多态性可用于亲子鉴定,累积排除率(CE值)为70%, Essen-Möller值为9.35(对数)。

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