线粒体肌病和脑肌病的治疗。
The treatment of mitochondrial myopathies and encephalomyopathies.
作者信息
Peterson P L
机构信息
Department of Neurology, Wayne State University School of Medicine, Detroit, MI 48201, USA.
出版信息
Biochim Biophys Acta. 1995 May 24;1271(1):275-80. doi: 10.1016/0925-4439(95)00039-7.
PMID:7599220
Abstract
This paper briefly summarizes the results of a long-term, open pharmacotherapy trial in 16 patients with well-characterized mitochondrial disease. Outcome measures included repeated clinical evaluation, 31P-NMR spectroscopy and near-infrared spectroscopy. Treated patients appeared to survive longer with less functional disability and medical complications than typically seen in clinical practice.
摘要
本文简要总结了一项针对16例特征明确的线粒体疾病患者的长期开放性药物治疗试验结果。观察指标包括反复的临床评估、31P核磁共振波谱法和近红外光谱法。与临床实践中常见情况相比，接受治疗的患者似乎存活时间更长，功能残疾和医疗并发症更少。
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