Klinken C
CRNA. 1995 Feb;6(1):37-42.
The purpose of the study was to compare the duration of analgesia and the amount of supplemental postoperative analgesics required when morphine combined with bupivacaine was injected into the knee joint at the end of knee arthroscopy surgery. Varying tourniquet times of 0, 8, or 16 minutes were used after the injection. The variables examined were the duration of analgesia, and the amount of supplemental postoperative analgesics required in each subgroup. A sample of 45 subjects was recruited and studied from an outpatient surgery center. The 45 subjects were randomly assigned to one of three groups (n = 15). At the end of the procedure, morphine combined with bupivacaine was injected into the intraarticular space and the tourniquet was released or left on for an additional 8 or 16 minutes. The duration of analgesia and the amount of supplemental postoperative analgesics administered in a 24-hour period were measured. No statistical differences were found between groups. All patients received analgesia with no reported side effects. Increasing the tourniquet time had no effect on the duration of analgesia or the amount of supplemental narcotics required in the postoperative period.
本研究的目的是比较在膝关节镜手术结束时将吗啡与布比卡因联合注射入膝关节后镇痛的持续时间以及术后所需补充镇痛药物的量。注射后采用0、8或16分钟的不同止血带使用时间。所检查的变量为镇痛持续时间以及每个亚组中术后所需补充镇痛药物的量。从一个门诊手术中心招募了45名受试者并进行研究。这45名受试者被随机分配到三个组之一(每组n = 15)。在手术结束时,将吗啡与布比卡因联合注射入关节腔,然后松开止血带或再保留8或16分钟。测量了镇痛持续时间以及24小时内给予的术后补充镇痛药物的量。各组之间未发现统计学差异。所有患者均接受了镇痛治疗,且未报告有副作用。增加止血带使用时间对镇痛持续时间或术后所需补充麻醉药物的量没有影响。